Pyrimethamine, Artesunate & Sulfadoxine Tablets

Product Description

What is Artesunate, Sulphadoxine & Pyrimethamine Tablets?
Artesunate, Sulphadoxine and Pyrimethamine Tablet is a combination medication is given to treat malaria.
It contains sulfadoxine (a sulfonamide) and pyrimethamine (an antiprotozoal) and Artesunate.
Detailed information related to Artesunate, Sulphadoxine & Pyrimethamine Tabletss uses, side-effects, reviews, questions, interactions, and precautions is as follows:

Artesunate, Sulphadoxine & Pyrimethamine Tablets Uses
Artesunate, Sulphadoxine & Pyrimethamine Tablets is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

• Artesunate, Sulphadoxine and Pyrimethamine Tablet is the mixture is given to be effective in treating malaria caused by Plasmodium falciparum than that caused by P.
• vivax, that chloroquine is given effective, though within the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine and therefore the combination could also be indicated the first-line treatment for children or adults with severe malaria, usually together with another antimalarial.

Artesunate, Sulphadoxine & Pyrimethamine Tablets Working, Mechanism of Action and Pharmacology
Artesunate, Sulphadoxine & Pyrimethamine Tablets improves the patient’s condition by performing the following functions:

• Artesunate is a prodrug thass rapidly converted to its active form dihydroartemisinin (DHA). This process involves the hydrolysis of the 4-carbon ester group via plasma esterase enzyme.
• It’s hypothesized that the cleavage of the endoperoxide bridge within the pharmacophore of DHA generates reactive oxygen species (ROS), which increases oxidative stress and causes malarial protein damage via alkylation.
• Sulfadoxine is a sulfonamide antibiotic that competes with p-aminobenzoic acid within the biosynthesis of folate. Pyrimethamine is a selective inhibitor of protozoal dihydrofolate reductase, hence preventing the synthesis of tetrahydrofolate the active sort of folate.

Artesunate, Sulphadoxine & Pyrimethamine Tablets Side-effects
The following is a list of possible side-effects that may occur from all constituting ingredients of Artesunate, Sulphadoxine & Pyrimethamine Tablets. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

• Hypersensitivity reactions (e.g. itchiness, dermatitis, and hives)
• Myelosuppression
• Gastrointestinal effects (e.g. nausea, vomiting, and diarrhoea)
• Headache